Global Cell Line Development
Market Report
2024
The Global Cell Line Development market is USD 5.2 billion in 2023 and will expand at a compound annual growth rate (CAGR) of 10.50% from 2023 to 2030.
The base year for the calculation is 2023 and 2019 to 2023 will be historical period. The year 2024 will be estimated one while the forecasted data will be from year 2025 to 2031. When we deliver the report that time we updated report data till the purchase date.
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The global cell line development market was valued at USD XX million in 2024. It is estimated to reach USD XX million by 2031, growing at a CAGR OF XX% during the forecast period (2024-2031).
• The global cell line development market will expand significantly by XX% CAGR between 2024 and 2031.
• Biotech and Pharmaceutical Companies dominate the market by being the end users.
• The major focus for cell line development is to discover ways for chronic disease treatment.
• North America is the largest cell line development shareholder and is estimated to grow at a CAGR of XX% over the forecast period.
Base Year | 2023 |
Historical Data Time Period | 2019-2023 |
Forecast Period | 2024-2031 |
Global Cell Line Development Market Sales Revenue 2023 | $ 5.2 Billion |
Global Cell Line Development Market Compound Annual Growth Rate (CAGR) for 2024 to 2031 | 10.5% |
North America Cell Line Development Market Compound Annual Growth Rate (CAGR) for 2024 to 2031 | 9.2% |
Europe Cell Line Development Market Compound Annual Growth Rate (CAGR) for 2024 to 2031 | 9.5% |
Asia Pacific Cell Line Development Market Compound Annual Growth Rate (CAGR) for 2024 to 2031 | 12% |
South America Cell Line Development Market Compound Annual Growth Rate (CAGR) for 2024 to 2031 | 10% |
Middle East and Africa Cell Line Development Market Compound Annual Growth Rate (CAGR) for 2024 to 2031 | 10.1% |
Market Split by Product |
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Market Split by Application |
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Market Split by Source |
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Market Split by End User |
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List of Competitors |
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Regional Analysis |
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Country Analysis |
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Key Qualitative Information Covered |
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Cell Line Development Market is Segmented as below. Particular segment of your interest can be provided without any additional cost. Download the Sample Pages!
The primary factors influencing the growth of the cell line development market are the expanding global patient pool, improving R&D capabilities, and increased public and private investment in the construction of healthcare infrastructure, particularly in emerging nations. Some of the most important steps in the cell line development process are gene cloning and transfection, clone selection, confirmatory analytics, cell line characterization, expansion, and downstream evaluation. A labour-intensive and complex process, the careful selection and validation of high-producing clones ensures the consistency and quality of the biological products. Cell line generation and verification are difficult, expensive processes requiring a variety of specialized knowledge research. The cell line development industry is very competitive and has a significant number of participants, both major and small. Numerous biotechnology, pharmaceutical, academic, and research institutes employ cell lines, as do diagnostic labs. Businesses and academic establishments are working to create more efficient methods that will enable them to produce stable, high-yielding cell lines. For instance, according to the Spy Biotech Licensed Selexis adopted Best-in-Class Cell Line Development Technologies to advance human cytomegalovirus VLP vaccine program.
Increase in the prevalence of cancer across the globe is leading to increased adoption of cell line development
The increase in the prevalence of cancer in low-income and middle-income countries is one of the major drivers for the cell line development market to grow. According to WHO (World Health Organization), 20 million new cases of cancer and 9.7 million deaths from cancer were reported in 2022. It was projected that 53.5 million people would still be alive five years after receiving a cancer diagnosis. One in five people will have cancer at some point in their lives; one in nine men and one in twelve women will pass away from the illness. Furthermore, it also said that It is anticipated that there will be over 35 million new cases of cancer in 2050, a 77% increase over the projected 20 million cases in 2022. Global warming and unhealthy lifestyles are the two main factors contributing to the increase in cancer cases. The development of cell lines is essential for the production of both therapeutic monoclonal antibodies and novel antibody-based therapies. Consequently, the increase in cancer subtypes, the use of targeted medications, and the creation of novel technologies for cell line generation will spur business expansion. (Source:https://www.who.int)
The research and development of new medications is called pharmaceutical R&D. Finding the target, which is frequently the location of a cell's receptor that a medicinal molecule may be able to influence, is the first stage in the procedure. With the rise in chronic diseases worldwide and the development of new diseases, the cell line development market has grown. According to research by Deloitte in 2022, the top 20 global pharmaceutical companies collectively spent $139bn on R&D. Fundamentally, the two primary facets of pharmaceutical R&D are pre-clinical research and the creation of innovative pharmaceuticals. clinical trials to assess prescription drugs. preparing and applying for approval from the Food and Drug Administration. Today, there is a far greater need than ever to change the direction and pace of research and development. Several converging dynamics are placing enormous pressure on R&D companies to boost their production of innovative drugs. New targets and modalities are being made possible by scientific discoveries, creating a world of opportunities to address unmet needs. (Source:https://www2.deloitte.com/uk/en/pages/press-releases/articles)
A significant step that frequently takes place on the critical route in the biopharmaceutical development process is cell line development. If the lead clone is not fully described during the initial screening phase, it could pose a threat to the viability of commercial production and result in considerable delays in the project's scale-up. On the other hand, it's thought that developing these innovative items for manufacturing is costly and challenging. The total estimation for the manufacturing development cost would be estimated at £1,201,016 for CTLs and £494,456 for PSCs. Most costs were accrued in the facility domain (56% and 51%), followed by personnel (20% and 32%), materials (19% and 15%) and equipment (4% and 2%). Additionally, in the pharma field, there is a lack of skilled staff which would play a key role in the development. As technology is increasing, it is expected that pharma staff adapt to the use and help in cell line development.
Research and development operations were impacted by supply chain disruptions, transportation restrictions, and the emphasis on healthcare demands. Workflow issues and delays in cell line production programs plagued the labs. However, the pandemic also highlighted the significance of cell-based research in the fight for treatments and vaccines. The cell development business gained from COVID-19 because it raised interest in vaccine research. Through the adoption of remote work and the use of technology to foster teamwork, the market has demonstrated its resilience. With the use of technological advancements cell line production was happening. For instance, according to NCBI, data of March 2022, a high throughput screening assay for inhibitors of SARS-CoV-2 pseudotyped particle entry was developed. The cell line is human and can be used for high-throughput testing of antiviral medications that target the coronavirus 2 that causes SARS-CoV-2, or severe acute respiratory syndrome. Angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) are two essential host proteins required for viral entry, and the human lung cancer cell line A549 was created to display high amounts of both of these proteins. As a result, several cell lines were developed to control COVID-19, which is still produced today and has had a big effect on the market during the pandemic. For instance, according to NCBI (National Center for Biotechnology Information), new testing procedures that made use of the CRISPR/CAS system's distinct RNA and DNA targeting capabilities to detect viral particles were created to battle the novel virus. It was also suggested to use the same CRISPR/CAS technique to replicate COVID-19 in cell lines. This made it possible for researchers and pharmaceutical companies to carry out in vivo studies to determine the mechanism by which the SARS-CoV-2 virus causes COVID-19, as well as drug screening assays.
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There are several large participants in the somewhat competitive cell line development business. Few businesses control the majority of the market. The market's participants are always working to make discoveries and contribute fresh research to medical studies and the healthcare sector. The development of vaccinations or medications that can be used to prevent chronic diseases is another area of attention for market participants.
Top Companies Market Share in Cell Line Development Industry: (In no particular order of Rank)
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According to Cognitive Market Research, North America dominated the market in 2023. It accounted for around 41% of the global revenue, owing to the region's robust research activities, well-established biopharmaceutical companies, and advanced healthcare infrastructure. The region's leadership is attributed to a high demand for biologics, increasing investments in drug development, and a favorable regulatory environment. The United States, in particular, stands out as a key player with a strong focus on biotechnology and pharmaceutical advancements. Additionally, collaborations between academic institutions and industry players contribute to the region's innovation. North America's prominent position in the cell line development market is expected to persist, driven by ongoing technological advancements and a continuous emphasis on biopharmaceutical research and development.
Europe is the fastest-growing category as the region's research and development activities increase, particularly in the pharmaceutical and biotechnology sectors. The region's advanced healthcare infrastructure and supportive regulatory environment make it prominent in cell line development. Collaborations between academic institutions and industry players further fuel innovation. Germany, the United Kingdom, and France emerge as key contributors to the market, hosting numerous biopharmaceutical companies and research centers. The demand for personalized medicine and biologics continues to propel cell line development activities, fostering a competitive landscape in Europe. Additionally, strategic partnerships and investments in emerging technologies enhance the region's position as a significant global cell line development market player.
The current report Scope analyzes Cell Line Development Market on 5 major region Split (In case you wish to acquire a specific region edition (more granular data) or any country Edition data then please write us on info@cognitivemarketresearch.com
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According to Cognitive Market Research, North America held the major market share in 2023. It accounted for more than 41% and a CAGR of 9.2% of the global revenue due to the increasing demand for biopharmaceuticals, the rising prevalence of chronic diseases, and advancements in cell-based research and therapy. North America's robust research infrastructure and supportive regulatory environment contribute significantly to market expansion. The region's emphasis on innovation and cutting-edge technologies further accelerates cell line development, fostering a dynamic and competitive market landscape. The market is driven by increasing demand for biopharmaceuticals and advancements in cell culture technologies. North America, a significant contributor to this growth, is characterized by a strong presence of pharmaceutical and biotechnology companies. The segment's expansion is fueled by continuous research and development activities, fostering innovation in cell line development for therapeutic applications.
According to Cognitive Market Research, The European Cell Line Development market accounted for approximately 30% and a CAGR of 9.5% of the global revenue due to the increasing demand for biopharmaceuticals, genetic engineering advancements, and rising research and development investments. Robust infrastructure, a skilled workforce, and supportive regulatory frameworks in Europe further contribute to market growth. As the pharmaceutical industry expands, the cell line development market is poised for sustained progression, fueled by the need for efficient and scalable biologics production. Increasing demand for biopharmaceuticals and rising investment in research and development are key factors propelling market expansion. The market is segmented based on type, application, and end-user, catering to diverse industry needs. Robust infrastructure, technological innovation, and collaborative efforts contribute to Europe's prominence in this dynamic market, fostering advancements in cell line development for therapeutic and research purposes.
According to Cognitive Market Research, Asia Pacific held a considerable market share in 2023, accounting for more than 20% and a CAGR of 12.0% of the global revenue due to the region's increasing research and development activities, rising demand for biopharmaceuticals and growing investments in the life sciences sector. Asia-Pacific's robust infrastructure, skilled workforce, and supportive regulatory environment fuel the market's momentum, making it a hotspot for cell line development innovations and advancements. The market encompasses various segments, including pharmaceuticals, biotechnology, and research institutions. Asia-Pacific's contribution to this market is driven by increasing investments in healthcare and biotechnology, rising R&D activities, and a growing emphasis on personalized medicine. The diverse segments within this region's cell line development market highlight the industry's dynamic nature and its potential for innovation and advancements.
According to Cognitive Market Research, Latin America accounted for more than 5% and a CAGR of 10.0% of the global Cell Line Development revenue in 2023 due to the region's increasing biopharmaceutical research and development activities, rising demand for personalized medicine, and supportive regulatory frameworks. The growing prevalence of chronic diseases and the expanding biotechnology sector fuel the demand for cell line development, positioning Latin America as a promising market with significant growth potential. The market encompasses various segments, including recombinant, hybridomas, and continuous cell lines. Factors such as increased biopharmaceutical research and development activities, rising demand for personalized medicine, and advancements in cell line engineering contribute to the market expansion. Latin America's growing importance in this sector reflects the region's increasing participation in biotechnology and pharmaceutical innovations, making it a focal point for industry players and investors.
According to Cognitive Market Research, The Middle East and Africa accounted for more than 4.50% and a CAGR of 10.1% of the global revenue in 2023 due to the increasing demand for biopharmaceuticals, driving the need for efficient and scalable cell line development processes. The region's rising focus on healthcare infrastructure and biotechnology advancements further propels market growth, fostering a dynamic landscape for cell line development in the Middle East and Africa.Key segments encompass primary cell lines, continuous cell lines, and recombinant cell lines. Technological advancements, rising investments in research and development, and the expanding biopharmaceutical industry contribute to market expansion. This dynamic landscape underscores the significance of cell line development in the pharmaceutical and biotechnology sectors, fostering innovation and therapeutic advancements.
Global Cell Line Development Market Report 2024 Edition talks about crucial market insights with the help of segments and sub-segments analysis. In this section, we reveal an in-depth analysis of the key factors influencing Cell Line Development Industry growth. Cell Line Development market has been segmented with the help of its Product , Application Source, and others. Cell Line Development market analysis helps to understand key industry segments, and their global, regional, and country-level insights. Furthermore, this analysis also provides information pertaining to segments that are going to be most lucrative in the near future and their expected growth rate and future market opportunities. The report also provides detailed insights into factors responsible for the positive or negative growth of each industry segment.
By Product Analysis
The global cell line development market is divided into reagents and media, equipment, and finished cells. The reagents and media are the highest shareholder of the market share and are expected to grow at CAGR XX% during the forecast period. Reagents and media are necessary when growing cells outside of their native habitat, which is usually done in a laboratory. These substances provide the environment, nutrition, and growth factors that cells require to mature and multiply. The specific requirements of the cells that need to be grown and multiplied dictate the equipment that is used. But for the procedures involved in creating cell lines, a few essential pieces of equipment are required, including autoclaves, incubators, centrifuges, microscopes, cell counts, freezers and refrigerators, and cell culture hoods. For the cell line to grow and remain viable, each is necessary.
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By Application
The market share is held by bioproduction and is expected to grow at CAGR XX% during the forecast period. The rise in bioproduction is due to the increasing number of chronic diseases which have caused high-quality biologics. For instance, according to OECD, The OECD reports that, based on age-standardized data, the United States, Mexico, and Turkey have the highest prevalence rates of adult diabetes among its member nations (with over 10% of the population living with the condition). Among OECD partner nations with diabetes prevalence rates of 10% or higher include South Africa, India, and Brazil. Therefore, the need for solutions for such diseases becomes important.
(Souce:https://www.oecdilibrary.org/sites/908b2da3en/index.html?itemId=/content/component/908b2da3-en)
Tissue engineering is a fast-growing field of study that uses cell line generation technology to replace, repair, or regenerate tissues or organs. The expanding application of cell line production methods in tissue engineering and regenerative medicine is the main factor propelling the segment's rise. Furthermore, by using cell line technology to encourage tissue-specific regeneration processes, tissue engineering seeks to eliminate the negative aspects of organ transplantation, such as the lack of available donors and the requirement for immunosuppressive treatment. It's something that helps the segment grow.
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By Source
Mammalian cell lines hold the market share and are expected to grow at CAGR XX% during the forecast period. This is a consequence of the growing use of sources of mammalian cells in the manufacturing of monoclonal antibodies. Mammalian cells are significantly more sophisticated as individual cells than bacterial ones since they are eukaryotic. These cell lines create complex proteins that are identical to those produced by the human body, which aids in the development of specific medications. Furthermore, biological components like human tissues can easily adapt to mammalian cell lines, reducing the risk of infection. A March 2022 study titled "Methods for transient expression and purification of monoclonal antibodies in mammalian cells" in Advances in Protein Molecular and Structural Biology Methods describes how human antibodies made in mice or rabbits can be transformed from polyclonal to monoclonal antibodies (mAbs), then chimeric to fully humanized mAbs. Human antibodies are now a sought-after therapeutic tool for usage in clinical and academic environments as a result of this technique. Improved mammalian cell line development to generate monoclonal antibodies—which are used to treat a variety of chronic diseases—is therefore anticipated to drive the segment's expansion.
By End User
Biotech and Pharmaceutical Companies hold the major market share by application and are expected to grow at CAGR XX%. Pharma Companies use cell line development for medicine formation for all types of body types. For instance, A study titled "Expected Impact of Biosimilars on the Pharmaceutical Companies" published in the Iranian Journal of Medical Science in September 2021 found that the introduction of biosimilars in the European Union (EU) has increased patient access to these products in the markets of France, Germany, Italy, Spain, and the UK by 44%. It can be anticipated that in coming years the biotech and pharmaceutical companies will hold more share in the market.
(Souce: https://ijms.sums.ac.ir/article_47761.html)
Senior Research Associate at Cognitive Market Research
Manjiri Kanhere is an experienced market researcher focused on the Pharma & Healthcare industry. With over 3+ years of experience, She has worked with major pharmaceutical companies and healthcare providers, helping them to understand market trends, identify new business opportunities, and develop effective sales & marketing strategies. Her expertise lies in the ability to analyze complex data sets and deliver insights that drive business decisions. At Cognitive Market Research, she handles the market research related to Pharma and healthcare industry.
Manjiri Kanhere is an experienced market researcher focused on the Pharma & Healthcare industry. With over three years of experience, She has worked with major pharmaceutical companies and healthcare providers, helping them to understand market trends, identify new business opportunities, and develop effective sales & marketing strategies.
In her current role, Manjiri handles the market research related to Pharma and healthcare industry. Her passion lies in utilizing innovative approaches to distill complex information into strategic insights that empower organizations to make informed decisions.Manjiri remains an invaluable asset in the dynamic landscape of market research.
Our study will explain complete manufacturing process along with major raw materials required to manufacture end-product. This report helps to make effective decisions determining product position and will assist you to understand opportunities and threats around the globe.
The Global Cell Line Development Market is witnessing significant growth in the near future.
In 2023, the Reagent and Media segment accounted for noticeable share of global Cell Line Development Market and is projected to experience significant growth in the near future.
The Bioproduction segment is expected to expand at the significant CAGR retaining position throughout the forecast period.
Some of the key companies Promega Corporation , Sartorius AG and others are focusing on its strategy building model to strengthen its product portfolio and expand its business in the global market.
Please note, we have not disclose, all the sources consulted/referred during a market study due to confidentiality and paid service concern. However, rest assured that upon purchasing the service or paid report version, we will release the comprehensive list of sources along with the complete report and we also provide the data support where you can intract with the team of analysts who worked on the report.
Disclaimer:
Product | Reagent and Media, Equipment, Finished Cells, Other Products |
Application | Bioproduction, Hybridomas Technology, Vaccine Production, Drug Discovery, Tissue Engineering |
Source | Mammalian cell line, Non-Mammalian cell line |
End User | Biotech and Pharmaceutical Companies, Academics and Research Institutes, Other End Users |
List of Competitors | Promega Corporation, Danaher Corporation, Sartorius AG, Thermo Fisher Scientific, Merck KGaA., Lonza, Fujifilm Holdings Corporation, JSR Corporation, Horizon Discovery Ltd., Rentschler Biopharma SE |
This chapter will help you gain GLOBAL Market Analysis of Cell Line Development. Further deep in this chapter, you will be able to review Global Cell Line Development Market Split by various segments and Geographical Split.
Chapter 1 Global Market Analysis
Global Market has been segmented on the basis 5 major regions such as North America, Europe, Asia-Pacific, Middle East & Africa, and Latin America.
You can purchase only the Executive Summary of Global Market (2019 vs 2024 vs 2031)
Global Market Dynamics, Trends, Drivers, Restraints, Opportunities, Only Pointers will be deliverable
Chapter 2 North America Market Analysis
Chapter 3 Europe Market Analysis
Chapter 4 Asia Pacific Market Analysis
Chapter 5 South America Market Analysis
Chapter 6 Middle East and Africa Market Analysis
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Chapter 7 Top 10 Countries Analysis (Only Available with Corporate User License)
Competitor's Market Share and Revenue (Subject to Data Availability for Private Players)
Chapter 8 Competitor Analysis (Subject to Data Availability (Private Players))
(Subject to Data Availability (Private Players))
Data Subject to Availability as we consider Top competitors and their market share will be delivered.
Data Subject to Availability as we consider Top competitors and their market share will be delivered.
Data Subject to Availability as we consider Top competitors and their market share will be delivered.
Data Subject to Availability as we consider Top competitors and their market share will be delivered.
Data Subject to Availability as we consider Top competitors and their market share will be delivered.
Data Subject to Availability as we consider Top competitors and their market share will be delivered.
Data Subject to Availability as we consider Top competitors and their market share will be delivered.
Data Subject to Availability as we consider Top competitors and their market share will be delivered.
Data Subject to Availability as we consider Top competitors and their market share will be delivered.
Data Subject to Availability as we consider Top competitors and their market share will be delivered.
Chapter 9 Qualitative Analysis (Subject to Data Availability)
Segmentation Product Analysis 2019 -2031, will provide market size split by Product . This Information is provided at Global Level, Regional Level and Top Countries Level The report with the segmentation perspective mentioned under this chapters will be delivered to you On Demand. So please let us know if you would like to receive this additional data as well. No additional cost will be applicable for the same.
Chapter 10 Market Split by Product Analysis 2019 -2031
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Chapter 11 Market Split by Application Analysis 2019 -2031
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Chapter 12 Market Split by Source Analysis 2019 -2031
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Chapter 13 Market Split by End User Analysis 2019 -2031
This chapter helps you understand the Key Takeaways and Analyst Point of View of the global Cell Line Development market
Chapter 14 Research Findings
Here the analyst will summarize the content of entire report and will share his view point on the current industry scenario and how the market is expected to perform in the near future. The points shared by the analyst are based on his/her detailed in-depth understanding of the market during the course of this report study. You will be provided exclusive rights to interact with the concerned analyst for unlimited time pre purchase as well as post purchase of the report.
Why Reagent and Media have a significant impact on Cell Line Development market? |
What are the key factors affecting the Reagent and Media and Equipment of Cell Line Development Market? |
What is the CAGR/Growth Rate of Bioproduction during the forecast period? |
By type, which segment accounted for largest share of the global Cell Line Development Market? |
Which region is expected to dominate the global Cell Line Development Market within the forecast period? |
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